Block selected UserAgents for all vhosts

I want block a few bots and crawlers, which not respect robots.txt.
I think the best way is to create a new apache config-file in "/etc/httpd/conf.d/block_useragents.conf" and reload apache?

Content of block_useragents.conf:

<Directory "/var/www/vhosts/*">
RewriteEngine On
RewriteCond %{HTTP_USER_AGENT} ^.*(Agent1|Agent2|Agent3).*$ [NC]
RewriteCond %{REQUEST_URI} !^robots.txt
RewriteRule .* - [F]
</Directory>

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Would this work for all vhosts? Is...

Block selected UserAgents for all vhosts